Attenuating Oxidative Stress by Paeonol Protected against Acetaminophen-Induced Hepatotoxicity in Mice

Acetaminophen (APAP) overdose is the most frequent cause of drug-induced acute liver failure. The purpose of this study was to investigate whether paeonol protected against APAP-induced hepatotoxicity. Mice treated with paeonol (25, 50, 100 mg/kg) received 400 mg/kg acetaminophen intraperitoneally (...

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Detalles Bibliográficos
Autores principales: Ding, Yi, Li, Qing, Xu, Yuan, Chen, Yuning, Deng, Yue, Zhi, Feng, Qian, Ke
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2016
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4856301/
https://www.ncbi.nlm.nih.gov/pubmed/27144271
http://dx.doi.org/10.1371/journal.pone.0154375

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