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Identifying Network Perturbation in Cancer

We present a computational framework, called DISCERN (DIfferential SparsE Regulatory Network), to identify informative topological changes in gene-regulator dependence networks inferred on the basis of mRNA expression datasets within distinct biological states. DISCERN takes two expression datasets...

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Detalles Bibliográficos
Autores principales:	Grechkin, Maxim, Logsdon, Benjamin A., Gentles, Andrew J., Lee, Su-In
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2016
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4856318/ https://www.ncbi.nlm.nih.gov/pubmed/27145341 http://dx.doi.org/10.1371/journal.pcbi.1004888

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