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Zinc Stabilizes Shank3 at the Postsynaptic Density of Hippocampal Synapses

Shank3 is a postsynaptic density (PSD) scaffold protein of the Shank family. Here we use pre-embedding immunogold electron microscopy to investigate factors influencing the distribution of Shank3 at the PSD. In dissociated rat hippocampal cultures under basal conditions, label for Shank3 was concent...

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Detalles Bibliográficos
Autores principales: Tao-Cheng, Jung-Hwa, Toy, Dana, Winters, Christine A., Reese, Thomas S., Dosemeci, Ayse
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4856407/
https://www.ncbi.nlm.nih.gov/pubmed/27144302
http://dx.doi.org/10.1371/journal.pone.0153979