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Identification of approved drugs that inhibit the binding of amyloid β oligomers to ephrin type‐B receptor 2

Ephrin type‐B receptor 2 (EphB2) is a member of the receptor tyrosine kinase family and plays an important role in learning and memory functions. In patients with Alzheimer's disease (AD) and in mouse models of AD, a reduction in the hippocampal EphB2 level is observed. It was recently reported...

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Detalles Bibliográficos
Autores principales: Suzuki, Koichiro, Aimi, Takahiro, Ishihara, Tomoaki, Mizushima, Tohru
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4856424/
https://www.ncbi.nlm.nih.gov/pubmed/27419051
http://dx.doi.org/10.1002/2211-5463.12056