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A membrane‐bound esterase PA2949 from Pseudomonas aeruginosa is expressed and purified from Escherichia coli

Pseudomonas aeruginosa strain 1001 produces an esterase (EstA) that can hydrolyse the racemic methyl ester of β‐acetylthioisobutyrate to produce the (D)‐enantiomer, which serves as a precursor of captopril, a drug used for treatment of hypertension. We show here that PA2949 from P. aeruginosa PA01,...

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Detalles Bibliográficos
Autores principales: Kovacic, Filip, Bleffert, Florian, Caliskan, Muttalip, Wilhelm, Susanne, Granzin, Joachim, Batra‐Safferling, Renu, Jaeger, Karl‐Erich
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4856427/
https://www.ncbi.nlm.nih.gov/pubmed/27419054
http://dx.doi.org/10.1002/2211-5463.12061