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Sero-epidemiological survey and risk factors associated with brucellosis in dogs in south-western Nigeria
INTRODUCTION: In Nigeria, there is limited information on brucellosis particularly in dogs, despite its public health implications. We undertook a sero-epidemiological survey of brucellosis in dogs to determine the prevalence of the disease and associated risk factors for its occurrence in Nigeria....
Autores principales: | , , , , , , , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
The African Field Epidemiology Network
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4856509/ https://www.ncbi.nlm.nih.gov/pubmed/27200134 http://dx.doi.org/10.11604/pamj.2016.23.29.7794 |
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author | Ayoola, Modupe Comfort Ogugua, Akwoba Joseph Akinseye, Victor Oluwatoyin Joshua, Tunde Olu Banuso, Morenikeji Folusho Adedoyin, Folashade Julianah Adesokan, Hezekiah Kehinde Omobowale, Temidayo Olutayo Abiola, John Olusoji Otuh, Patricia Ihuaku Nottidge, Helen Oyebukola Dale, Emma-Jane Perrett, Lorraine Taylor, Andrew Stack, Judy Cadmus, Simeon Idowu Babalola |
author_facet | Ayoola, Modupe Comfort Ogugua, Akwoba Joseph Akinseye, Victor Oluwatoyin Joshua, Tunde Olu Banuso, Morenikeji Folusho Adedoyin, Folashade Julianah Adesokan, Hezekiah Kehinde Omobowale, Temidayo Olutayo Abiola, John Olusoji Otuh, Patricia Ihuaku Nottidge, Helen Oyebukola Dale, Emma-Jane Perrett, Lorraine Taylor, Andrew Stack, Judy Cadmus, Simeon Idowu Babalola |
author_sort | Ayoola, Modupe Comfort |
collection | PubMed |
description | INTRODUCTION: In Nigeria, there is limited information on brucellosis particularly in dogs, despite its public health implications. We undertook a sero-epidemiological survey of brucellosis in dogs to determine the prevalence of the disease and associated risk factors for its occurrence in Nigeria. METHODS: A cross-sectional study was conducted to screen dogs in south-western Nigeria for antibodies to Brucella sp using the rapid slide agglutination test (RSA) and Rose Bengal test (RBT), with positive samples confirmed respectively by serum agglutination test (SAT) and competitive enzyme linked immunosorbent assay (cELISA). Data were analyzed with STATA-12. RESULTS: From the 739 dog sera tested, 81 (10.96%) were positive by RSA and 94 (12.72%) by RBT; these were corroborated with SAT (4/81; 4.94%) and cELISA (1/94; 1.06%), respectively. Logistic regression identified location (OR=0.04; 95% CI: 0.02-0.09), breed (OR=1.71; 95% CI: 1.34-2.19), age (OR=0.10; 95% CI: 0.04-0.30) and management system (OR=8.51; 95% CI: 1.07-68.05) as risk factors for Brucella infection by RSA. However, location (OR=10.83; 95% CI: 5.48-21.39) and history of infertility (OR=2.62; 95% CI: 1.41-4.84) were identified as risk factors using RBT. CONCLUSION: Given the 10.96% to 12.72% seroprevalence of brucellosis recorded in this study, we advocate control of the disease in dogs, and public health education for those at risk of infection. Again, further studies are required to elucidate the role of dogs in the epidemiology of brucellosis in Nigeria considering the conducive human-animal interface and ecological factors responsible for the transmission of the disease. |
format | Online Article Text |
id | pubmed-4856509 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2016 |
publisher | The African Field Epidemiology Network |
record_format | MEDLINE/PubMed |
spelling | pubmed-48565092016-05-19 Sero-epidemiological survey and risk factors associated with brucellosis in dogs in south-western Nigeria Ayoola, Modupe Comfort Ogugua, Akwoba Joseph Akinseye, Victor Oluwatoyin Joshua, Tunde Olu Banuso, Morenikeji Folusho Adedoyin, Folashade Julianah Adesokan, Hezekiah Kehinde Omobowale, Temidayo Olutayo Abiola, John Olusoji Otuh, Patricia Ihuaku Nottidge, Helen Oyebukola Dale, Emma-Jane Perrett, Lorraine Taylor, Andrew Stack, Judy Cadmus, Simeon Idowu Babalola Pan Afr Med J Research INTRODUCTION: In Nigeria, there is limited information on brucellosis particularly in dogs, despite its public health implications. We undertook a sero-epidemiological survey of brucellosis in dogs to determine the prevalence of the disease and associated risk factors for its occurrence in Nigeria. METHODS: A cross-sectional study was conducted to screen dogs in south-western Nigeria for antibodies to Brucella sp using the rapid slide agglutination test (RSA) and Rose Bengal test (RBT), with positive samples confirmed respectively by serum agglutination test (SAT) and competitive enzyme linked immunosorbent assay (cELISA). Data were analyzed with STATA-12. RESULTS: From the 739 dog sera tested, 81 (10.96%) were positive by RSA and 94 (12.72%) by RBT; these were corroborated with SAT (4/81; 4.94%) and cELISA (1/94; 1.06%), respectively. Logistic regression identified location (OR=0.04; 95% CI: 0.02-0.09), breed (OR=1.71; 95% CI: 1.34-2.19), age (OR=0.10; 95% CI: 0.04-0.30) and management system (OR=8.51; 95% CI: 1.07-68.05) as risk factors for Brucella infection by RSA. However, location (OR=10.83; 95% CI: 5.48-21.39) and history of infertility (OR=2.62; 95% CI: 1.41-4.84) were identified as risk factors using RBT. CONCLUSION: Given the 10.96% to 12.72% seroprevalence of brucellosis recorded in this study, we advocate control of the disease in dogs, and public health education for those at risk of infection. Again, further studies are required to elucidate the role of dogs in the epidemiology of brucellosis in Nigeria considering the conducive human-animal interface and ecological factors responsible for the transmission of the disease. The African Field Epidemiology Network 2016-02-04 /pmc/articles/PMC4856509/ /pubmed/27200134 http://dx.doi.org/10.11604/pamj.2016.23.29.7794 Text en © Ayoola Modupe Comfort et al. http://creativecommons.org/licenses/by/2.0/ The Pan African Medical Journal - ISSN 1937-8688. This is an Open Access article distributed under the terms of the Creative Commons Attribution License which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. |
spellingShingle | Research Ayoola, Modupe Comfort Ogugua, Akwoba Joseph Akinseye, Victor Oluwatoyin Joshua, Tunde Olu Banuso, Morenikeji Folusho Adedoyin, Folashade Julianah Adesokan, Hezekiah Kehinde Omobowale, Temidayo Olutayo Abiola, John Olusoji Otuh, Patricia Ihuaku Nottidge, Helen Oyebukola Dale, Emma-Jane Perrett, Lorraine Taylor, Andrew Stack, Judy Cadmus, Simeon Idowu Babalola Sero-epidemiological survey and risk factors associated with brucellosis in dogs in south-western Nigeria |
title | Sero-epidemiological survey and risk factors associated with brucellosis in dogs in south-western Nigeria |
title_full | Sero-epidemiological survey and risk factors associated with brucellosis in dogs in south-western Nigeria |
title_fullStr | Sero-epidemiological survey and risk factors associated with brucellosis in dogs in south-western Nigeria |
title_full_unstemmed | Sero-epidemiological survey and risk factors associated with brucellosis in dogs in south-western Nigeria |
title_short | Sero-epidemiological survey and risk factors associated with brucellosis in dogs in south-western Nigeria |
title_sort | sero-epidemiological survey and risk factors associated with brucellosis in dogs in south-western nigeria |
topic | Research |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4856509/ https://www.ncbi.nlm.nih.gov/pubmed/27200134 http://dx.doi.org/10.11604/pamj.2016.23.29.7794 |
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