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HIV-Nef and ADAM17-Containing Plasma Extracellular Vesicles Induce and Correlate with Immune Pathogenesis in Chronic HIV Infection

Antiretroviral therapy (ART) efficiently suppresses HIV replication but immune activation and low CD4 T cell counts often persist. The underlying mechanism of this ART-resistant pathogenesis is not clear. We observed that levels of plasma extracellular vesicles (pEV) are strongly elevated in HIV inf...

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Detalles Bibliográficos
Autores principales:	Lee, Jung-Hyun, Schierer, Stephan, Blume, Katja, Dindorf, Jochen, Wittki, Sebastian, Xiang, Wei, Ostalecki, Christian, Koliha, Nina, Wild, Stefan, Schuler, Gerold, Fackler, Oliver T., Saksela, Kalle, Harrer, Thomas, Baur, Andreas S.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Elsevier 2016
Materias:	Research Paper
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4856776/ https://www.ncbi.nlm.nih.gov/pubmed/27211553 http://dx.doi.org/10.1016/j.ebiom.2016.03.004

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