Expression of microRNAs in HPV negative tonsil cancers and their regulation of PDCD4

Global rates of tonsil cancer have been increasing since the turn of the millennia, however we still have a limited understanding of the genes and pathways which control this disease. This array dataset which is linked to our publication (Zhang et al., 2015) describes the profiling of human miRNAs i...

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Detalles Bibliográficos
Autores principales: Khoury, Samantha, Ahadi, Alireza, Zhang, Xiaoying, Tran, Nham
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2016
Materias:
Data in Brief
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4856814/
https://www.ncbi.nlm.nih.gov/pubmed/27222808
http://dx.doi.org/10.1016/j.gdata.2016.04.007
Descripción
Sumario:Global rates of tonsil cancer have been increasing since the turn of the millennia, however we still have a limited understanding of the genes and pathways which control this disease. This array dataset which is linked to our publication (Zhang et al., 2015) describes the profiling of human miRNAs in tonsil and normal adjacent tissues. With this dataset, we identified a list of microRNA (miRNA) which were highly over represented in tonsil cancers and showed that several miRNAs were able to regulate the tumour suppressor PDCD4 in a temporal manner. The dataset has been deposited into Gene Expression Omnibus (GSE75630).

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