Expression of microRNAs in HPV negative tonsil cancers and their regulation of PDCD4

Global rates of tonsil cancer have been increasing since the turn of the millennia, however we still have a limited understanding of the genes and pathways which control this disease. This array dataset which is linked to our publication (Zhang et al., 2015) describes the profiling of human miRNAs i...

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Autores principales: Khoury, Samantha, Ahadi, Alireza, Zhang, Xiaoying, Tran, Nham
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2016
Materias:
Data in Brief
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4856814/
https://www.ncbi.nlm.nih.gov/pubmed/27222808
http://dx.doi.org/10.1016/j.gdata.2016.04.007
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author Khoury, Samantha
Ahadi, Alireza
Zhang, Xiaoying
Tran, Nham
author_facet Khoury, Samantha
Ahadi, Alireza
Zhang, Xiaoying
Tran, Nham
author_sort Khoury, Samantha
collection PubMed
description Global rates of tonsil cancer have been increasing since the turn of the millennia, however we still have a limited understanding of the genes and pathways which control this disease. This array dataset which is linked to our publication (Zhang et al., 2015) describes the profiling of human miRNAs in tonsil and normal adjacent tissues. With this dataset, we identified a list of microRNA (miRNA) which were highly over represented in tonsil cancers and showed that several miRNAs were able to regulate the tumour suppressor PDCD4 in a temporal manner. The dataset has been deposited into Gene Expression Omnibus (GSE75630).
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spelling pubmed-48568142016-05-24 Expression of microRNAs in HPV negative tonsil cancers and their regulation of PDCD4 Khoury, Samantha Ahadi, Alireza Zhang, Xiaoying Tran, Nham Genom Data Data in Brief Global rates of tonsil cancer have been increasing since the turn of the millennia, however we still have a limited understanding of the genes and pathways which control this disease. This array dataset which is linked to our publication (Zhang et al., 2015) describes the profiling of human miRNAs in tonsil and normal adjacent tissues. With this dataset, we identified a list of microRNA (miRNA) which were highly over represented in tonsil cancers and showed that several miRNAs were able to regulate the tumour suppressor PDCD4 in a temporal manner. The dataset has been deposited into Gene Expression Omnibus (GSE75630). Elsevier 2016-04-18 /pmc/articles/PMC4856814/ /pubmed/27222808 http://dx.doi.org/10.1016/j.gdata.2016.04.007 Text en © 2016 The Authors http://creativecommons.org/licenses/by-nc-nd/4.0/ This is an open access article under the CC BY-NC-ND license (http://creativecommons.org/licenses/by-nc-nd/4.0/).
spellingShingle Data in Brief
Khoury, Samantha
Ahadi, Alireza
Zhang, Xiaoying
Tran, Nham
Expression of microRNAs in HPV negative tonsil cancers and their regulation of PDCD4
title Expression of microRNAs in HPV negative tonsil cancers and their regulation of PDCD4
title_full Expression of microRNAs in HPV negative tonsil cancers and their regulation of PDCD4
title_fullStr Expression of microRNAs in HPV negative tonsil cancers and their regulation of PDCD4
title_full_unstemmed Expression of microRNAs in HPV negative tonsil cancers and their regulation of PDCD4
title_short Expression of microRNAs in HPV negative tonsil cancers and their regulation of PDCD4
title_sort expression of micrornas in hpv negative tonsil cancers and their regulation of pdcd4
topic Data in Brief
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4856814/
https://www.ncbi.nlm.nih.gov/pubmed/27222808
http://dx.doi.org/10.1016/j.gdata.2016.04.007
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