Correlation of A2bAR and KLF4/KLF15 with Obesity-Dyslipidemia Induced Inflammation in Uygur Population

In this paper, the researchers collected visceral adipose tissue from the Uygur population, which were divided into two groups: the normal control group (NC, n = 50, 18.0 kg/m(2) ≤ BMI ≤ 23.9 kg/m(2)) and the obese group (OB, n = 45, BMI ≥ 28 kg/m(2)), and then use real-time PCR to detect the mRNA e...

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Autores principales: Wang, Cuizhe, Ha, Xiaodan, Li, Wei, Xu, Peng, Gu, Yajuan, Wang, Tingting, Wang, Yan, Xie, Jianxin, Zhang, Jun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi Publishing Corporation 2016
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4856914/
https://www.ncbi.nlm.nih.gov/pubmed/27199507
http://dx.doi.org/10.1155/2016/7015620
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author Wang, Cuizhe
Ha, Xiaodan
Li, Wei
Xu, Peng
Gu, Yajuan
Wang, Tingting
Wang, Yan
Xie, Jianxin
Zhang, Jun
author_facet Wang, Cuizhe
Ha, Xiaodan
Li, Wei
Xu, Peng
Gu, Yajuan
Wang, Tingting
Wang, Yan
Xie, Jianxin
Zhang, Jun
author_sort Wang, Cuizhe
collection PubMed
description In this paper, the researchers collected visceral adipose tissue from the Uygur population, which were divided into two groups: the normal control group (NC, n = 50, 18.0 kg/m(2) ≤ BMI ≤ 23.9 kg/m(2)) and the obese group (OB, n = 45, BMI ≥ 28 kg/m(2)), and then use real-time PCR to detect the mRNA expression level of key genes involved in inflammation signaling pathway. The findings suggest that, in obese status, the lower expression level of A2bAR, KLF4, and KLF15 of visceral adipose tissue may correlate with obese-dyslipidemia induced inflammation in Uygur population.
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spelling pubmed-48569142016-05-19 Correlation of A2bAR and KLF4/KLF15 with Obesity-Dyslipidemia Induced Inflammation in Uygur Population Wang, Cuizhe Ha, Xiaodan Li, Wei Xu, Peng Gu, Yajuan Wang, Tingting Wang, Yan Xie, Jianxin Zhang, Jun Mediators Inflamm Research Article In this paper, the researchers collected visceral adipose tissue from the Uygur population, which were divided into two groups: the normal control group (NC, n = 50, 18.0 kg/m(2) ≤ BMI ≤ 23.9 kg/m(2)) and the obese group (OB, n = 45, BMI ≥ 28 kg/m(2)), and then use real-time PCR to detect the mRNA expression level of key genes involved in inflammation signaling pathway. The findings suggest that, in obese status, the lower expression level of A2bAR, KLF4, and KLF15 of visceral adipose tissue may correlate with obese-dyslipidemia induced inflammation in Uygur population. Hindawi Publishing Corporation 2016 2016-04-21 /pmc/articles/PMC4856914/ /pubmed/27199507 http://dx.doi.org/10.1155/2016/7015620 Text en Copyright © 2016 Cuizhe Wang et al. https://creativecommons.org/licenses/by/4.0/ This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Research Article
Wang, Cuizhe
Ha, Xiaodan
Li, Wei
Xu, Peng
Gu, Yajuan
Wang, Tingting
Wang, Yan
Xie, Jianxin
Zhang, Jun
Correlation of A2bAR and KLF4/KLF15 with Obesity-Dyslipidemia Induced Inflammation in Uygur Population
title Correlation of A2bAR and KLF4/KLF15 with Obesity-Dyslipidemia Induced Inflammation in Uygur Population
title_full Correlation of A2bAR and KLF4/KLF15 with Obesity-Dyslipidemia Induced Inflammation in Uygur Population
title_fullStr Correlation of A2bAR and KLF4/KLF15 with Obesity-Dyslipidemia Induced Inflammation in Uygur Population
title_full_unstemmed Correlation of A2bAR and KLF4/KLF15 with Obesity-Dyslipidemia Induced Inflammation in Uygur Population
title_short Correlation of A2bAR and KLF4/KLF15 with Obesity-Dyslipidemia Induced Inflammation in Uygur Population
title_sort correlation of a2bar and klf4/klf15 with obesity-dyslipidemia induced inflammation in uygur population
topic Research Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4856914/
https://www.ncbi.nlm.nih.gov/pubmed/27199507
http://dx.doi.org/10.1155/2016/7015620
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