Role of TFEB Mediated Autophagy, Oxidative Stress, Inflammation, and Cell Death in Endotoxin Induced Myocardial Toxicity of Young and Aged Mice

Elderly patients are susceptible to sepsis. LPS induced myocardial injury is a widely used animal model to assess sepsis induced cardiac dysfunction. The age dependent mechanisms behind sepsis susceptibility were not studied. We analyzed age associated changes to cardiac function, cell death, inflam...

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Detalles Bibliográficos
Autores principales: Li, Fang, Lang, Fangfang, Zhang, Huilin, Xu, Liangdong, Wang, Yidan, Hao, Enkui
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi Publishing Corporation 2016
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4856916/
https://www.ncbi.nlm.nih.gov/pubmed/27200146
http://dx.doi.org/10.1155/2016/5380319

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