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FRET-based assay to screen inhibitors of HIV-1 reverse transcriptase and nucleocapsid protein

During HIV-1 reverse transcription, the single-stranded RNA genome is converted into proviral double stranded DNA by Reverse Transcriptase (RT) within a reverse transcription complex composed of the genomic RNA and a number of HIV-1 encoded proteins, including the nucleocapsid protein NCp7. Here, we...

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Detalles Bibliográficos
Autores principales:	Sharma, Kamal K., Przybilla, Frédéric, Restle, Tobias, Godet, Julien, Mély, Yves
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Oxford University Press 2016
Materias:	Methods Online
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4856972/ https://www.ncbi.nlm.nih.gov/pubmed/26762982 http://dx.doi.org/10.1093/nar/gkv1532

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