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COSMOS: accurate detection of somatic structural variations through asymmetric comparison between tumor and normal samples
An important challenge in cancer genomics is precise detection of structural variations (SVs) by high-throughput short-read sequencing, which is hampered by the high false discovery rates of existing analysis tools. Here, we propose an accurate SV detection method named COSMOS, which compares the st...
| Autores principales: | , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Oxford University Press
2016
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4856976/ https://www.ncbi.nlm.nih.gov/pubmed/26833260 http://dx.doi.org/10.1093/nar/gkw026 |