The downregulation of the RNA-binding protein Staufen2 in response to DNA damage promotes apoptosis

Staufen2 (Stau2) is an RNA-binding protein involved in cell fate decision by controlling several facets of mRNA processing including localization, splicing, translation and stability. Herein we report that exposure to DNA-damaging agents that generate replicative stress such as camptothecin (CPT), 5...

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Detalles Bibliográficos
Autores principales: Zhang, Xin, Trépanier, Véronique, Beaujois, Remy, Viranaicken, Wildriss, Drobetsky, Elliot, DesGroseillers, Luc
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2016
Materias:
Genome Integrity, Repair and Replication
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4856980/
https://www.ncbi.nlm.nih.gov/pubmed/26843428
http://dx.doi.org/10.1093/nar/gkw057

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