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Structural characterization of the virulence factor Sda1 nuclease from Streptococcus pyogenes

Infection by Group A Streptococcus pyogenes (GAS) is a leading cause of severe invasive disease in humans, including streptococcal toxic shock syndrome and necrotizing fasciitis. GAS infections lead to nearly 163,000 annual deaths worldwide. Hypervirulent strains of S. pyogenes have evolved a pletho...

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Detalles Bibliográficos
Autores principales:	Moon, Andrea F., Krahn, Juno M., Lu, Xun, Cuneo, Matthew J., Pedersen, Lars C.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Oxford University Press 2016
Materias:	Structural Biology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4856990/ https://www.ncbi.nlm.nih.gov/pubmed/26969731 http://dx.doi.org/10.1093/nar/gkw143

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