CRISPR-mediated control of the bacterial initiation of replication

Programmable control of the cell cycle has been shown to be a powerful tool in cell-biology studies. Here, we develop a novel system for controlling the bacterial cell cycle, based on binding of CRISPR/dCas9 to the origin-of-replication locus. Initiation of replication of bacterial chromosomes is ac...

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Detalles Bibliográficos
Autores principales: Wiktor, Jakub, Lesterlin, Christian, Sherratt, David J., Dekker, Cees
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2016
Materias:
Molecular Biology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4857001/
https://www.ncbi.nlm.nih.gov/pubmed/27036863
http://dx.doi.org/10.1093/nar/gkw214

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4857001/
https://www.ncbi.nlm.nih.gov/pubmed/27036863
http://dx.doi.org/10.1093/nar/gkw214

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