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Polymorphic tandem repeats within gene promoters act as modifiers of gene expression and DNA methylation in humans

Despite representing an important source of genetic variation, tandem repeats (TRs) remain poorly studied due to technical difficulties. We hypothesized that TRs can operate as expression (eQTLs) and methylation (mQTLs) quantitative trait loci. To test this we analyzed the effect of variation at 484...

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Detalles Bibliográficos
Autores principales:	Quilez, Javier, Guilmatre, Audrey, Garg, Paras, Highnam, Gareth, Gymrek, Melissa, Erlich, Yaniv, Joshi, Ricky S., Mittelman, David, Sharp, Andrew J.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Oxford University Press 2016
Materias:	Genomics
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4857002/ https://www.ncbi.nlm.nih.gov/pubmed/27060133 http://dx.doi.org/10.1093/nar/gkw219

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