FAM46 proteins are novel eukaryotic non-canonical poly(A) polymerases

FAM46 proteins, encoded in all known animal genomes, belong to the nucleotidyltransferase (NTase) fold superfamily. All four human FAM46 paralogs (FAM46A, FAM46B, FAM46C, FAM46D) are thought to be involved in several diseases, with FAM46C reported as a causal driver of multiple myeloma; however, the...

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Detalles Bibliográficos
Autores principales: Kuchta, Krzysztof, Muszewska, Anna, Knizewski, Lukasz, Steczkiewicz, Kamil, Wyrwicz, Lucjan S., Pawlowski, Krzysztof, Rychlewski, Leszek, Ginalski, Krzysztof
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2016
Materias:
Computational Biology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4857005/
https://www.ncbi.nlm.nih.gov/pubmed/27060136
http://dx.doi.org/10.1093/nar/gkw222

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4857005/
https://www.ncbi.nlm.nih.gov/pubmed/27060136
http://dx.doi.org/10.1093/nar/gkw222

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