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PfCRT and PfMDR1 modulate interactions of artemisinin derivatives and ion channel blockers

Treatment of the symptomatic asexual stage of Plasmodium falciparum relies almost exclusively on artemisinin (ART) combination therapies (ACTs) in endemic regions. ACTs combine ART or its derivative with a long-acting partner drug to maximize efficacy during the typical three-day regimen. Both labor...

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Detalles Bibliográficos
Autores principales:	Eastman, Richard T., Khine, Pwint, Huang, Ruili, Thomas, Craig J., Su, Xin-zhuan
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group 2016
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4857081/ https://www.ncbi.nlm.nih.gov/pubmed/27147113 http://dx.doi.org/10.1038/srep25379

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