Cargando…

Colorectal cancer risk genes are functionally enriched in regulatory pathways

Colorectal cancer (CRC) is a common complex disease caused by the combination of genetic variants and environmental factors. Genome-wide association studies (GWAS) have been performed and reported some novel CRC susceptibility variants. However, the potential genetic mechanisms for newly identified...

Descripción completa

Detalles Bibliográficos
Autores principales:	Lu, Xi, Cao, Mingming, Han, Su, Yang, Youlin, Zhou, Jin
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group 2016
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4857176/ https://www.ncbi.nlm.nih.gov/pubmed/27146020 http://dx.doi.org/10.1038/srep25347

Ejemplares similares

Functional Enrichment Analysis of Regulatory Elements
por: Garcia-Moreno, Adrian, et al.
Publicado: (2022)

An organ boundary-enriched gene regulatory network uncovers regulatory hierarchies underlying axillary meristem initiation
por: Tian, Caihuan, et al.
Publicado: (2014)

IBD risk loci are enriched in multigenic regulatory modules encompassing putative causative genes
por: Momozawa, Yukihide, et al.
Publicado: (2018)

Differential enrichment of regulatory motifs in the composite network of protein-protein and gene regulatory interactions
por: Hegde, Shubhada R, et al.
Publicado: (2014)

Enriching for direct regulatory targets in perturbed gene-expression profiles
por: Tringe, Susannah G, et al.
Publicado: (2004)

A stele-enriched gene regulatory network in the Arabidopsis root
por: Brady, Siobhan M, et al.
Publicado: (2011)

Tissue-Specific Enrichment of Lymphoma Risk Loci in Regulatory Elements
por: Hayes, James E., et al.
Publicado: (2015)

Microbial functional genes enriched in the Xiangjiang River sediments with heavy metal contamination
por: Jie, Shiqi, et al.
Publicado: (2016)

Identifying key genes and functionally enriched pathways in Th2-high asthma by weighted gene co-expression network analysis
por: Cao, Yao, et al.
Publicado: (2022)

Centrality-based pathway enrichment: a systematic approach for finding significant pathways dominated by key genes
por: Gu, Zuguang, et al.
Publicado: (2012)

Identifying Key Genes and Functionally Enriched Pathways of Diverse Adipose Tissue Types in Cattle
por: Pan, Cuili, et al.
Publicado: (2022)

EWS and FUS bind a subset of transcribed genes encoding proteins enriched in RNA regulatory functions
por: Luo, Yonglun, et al.
Publicado: (2015)

Potential Genes and Pathways of Neonatal Sepsis Based on Functional Gene Set Enrichment Analyses
por: Meng, YuXiu, et al.
Publicado: (2018)

Generation of Realistic Gene Regulatory Networks by Enriching for Feed-Forward Loops
por: Zhivkoplias, Erik K., et al.
Publicado: (2022)

Recent advances of γ-aminobutyric acid: Physiological and immunity function, enrichment, and metabolic pathway
por: Heli, Zhou, et al.
Publicado: (2022)

Identifying Key Genes and Functionally Enriched Pathways in Sjögren’s Syndrome by Weighted Gene Co-Expression Network Analysis
por: Yao, Qiuming, et al.
Publicado: (2019)

Systematic enrichment analysis of gene expression profiling studies identifies consensus pathways implicated in colorectal cancer development
por: Lascorz, Jesús, et al.
Publicado: (2011)

Genes related to emphysema are enriched for ubiquitination pathways
por: Stepaniants, Sergey, et al.
Publicado: (2014)

Transcriptome-wide gene-gene interaction associations elucidate pathways and functional enrichment of complex traits
por: Evans, Luke M., et al.
Publicado: (2023)

Nuclear paraspeckles function in mediating gene regulatory and apoptotic pathways
por: Pisani, Gabriel, et al.
Publicado: (2019)

PD-L1(+)CD8(+) T cells enrichment in lung cancer exerted regulatory function and tumor-promoting tolerance
por: Zheng, Yingxia, et al.
Publicado: (2022)

Pathway Enrichment Analysis with Networks
por: Liu, Lu, et al.
Publicado: (2017)

Genetic and functional interaction network analysis reveals global enrichment of regulatory T cell genes influencing basal cell carcinoma susceptibility
por: Adolphe, Christelle, et al.
Publicado: (2021)

CD4(+) T Cells Expressing Latency-Associated Peptide and Foxp3 Are an Activated Subgroup of Regulatory T Cells Enriched in Patients with Colorectal Cancer
por: Mahalingam, Jayashri, et al.
Publicado: (2014)

EasyGO: Gene Ontology-based annotation and functional enrichment analysis tool for agronomical species
por: Zhou, Xin, et al.
Publicado: (2007)

A Gene-Set Enrichment and Protein–Protein Interaction Network-Based GWAS with Regulatory SNPs Identifies Candidate Genes and Pathways Associated with Carcass Traits in Hanwoo Cattle
por: Srikanth, Krishnamoorthy, et al.
Publicado: (2020)

Consensus Pathways Implicated in Prognosis of Colorectal Cancer Identified Through Systematic Enrichment Analysis of Gene Expression Profiling Studies
por: Lascorz, Jesús, et al.
Publicado: (2011)

Foes or Friends? Bacteria Enriched in the Tumor Microenvironment of Colorectal Cancer
por: Xu, Siyang, et al.
Publicado: (2020)

Identification of uveitis-associated functions based on the feature selection analysis of gene ontology and Kyoto Encyclopedia of Genes and Genomes pathway enrichment scores
por: Lu, Shiheng, et al.
Publicado: (2022)

ceRNA Network and Functional Enrichment Analysis of Preeclampsia by Weighted Gene Coexpression Network Analysis
por: Wang, Chenxu, et al.
Publicado: (2022)

Enrichment of risk SNPs in regulatory regions implicate diverse tissues in Parkinson’s disease etiology
por: Coetzee, Simon G., et al.
Publicado: (2016)

Evolutionary conservation and over-representation of functionally enriched network patterns in the yeast regulatory network
por: Meshi, Ofer, et al.
Publicado: (2007)

Pathways Targeted by Antidiabetes Drugs Are Enriched for Multiple Genes Associated With Type 2 Diabetes Risk
por: Segrè, Ayellet V., et al.
Publicado: (2015)

The Regulatory Role of Neuropeptide Gene Glucagon in Colorectal Cancer: A Comprehensive Bioinformatic Analysis
por: Du, Wenfeng, et al.
Publicado: (2022)

Pathway-targeting gene matrix for Drosophila gene set enrichment analysis
por: Cheng, Jack, et al.
Publicado: (2021)

In-depth analysis of the critical genes and pathways in colorectal cancer
por: LIU, FUGUO, et al.
Publicado: (2015)

IL6-mediated HCoV-host interactome regulatory network and GO/Pathway enrichment analysis
por: Politano, Gianfranco, et al.
Publicado: (2020)

Transcriptomic Analysis of Colorectal Cancer Cells Treated with Oil Production Waste Products (OPWPs) Reveals Enrichment of Pathways of Mitochondrial Functionality
por: Leo, Manuela, et al.
Publicado: (2022)

Differentially Expressed Genes and Enriched Signaling Pathways in the Adipose Tissue of Obese People
por: Lu, Zhenhua, et al.
Publicado: (2021)

Survival-related genes are diversified across cancers but generally enriched in cancer hallmark pathways
por: Wang, Po-Wen, et al.
Publicado: (2022)

Cannot write session to /tmp/vufind_sessions/sess_o7ajfafl5aoulh6ok9tib25oae