A protracted course of Pneumocystis pneumonia in the setting of an immunosuppressed child with GMS-negative bronchoalveolar lavage

We report a case of Pneumocystis pneumonia in a 5-year-old male with Trisomy 21 and acute lymphoblastic leukemia. The lack of response to trimethoprim-sulfamethoxazole raised concerns for antimicrobial resistance. Further, diagnosis of Pneumocystis in this patient was complicated by a GMS-negative b...

Descripción completa

Detalles Bibliográficos
Autores principales: Eddens, Taylor, Song, Eunkyung, Ardura, Monica I., Kolls, Jay K.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2016
Materias:
Case Report
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4857217/
https://www.ncbi.nlm.nih.gov/pubmed/27182485
http://dx.doi.org/10.1016/j.mmcr.2016.04.004
_version_ 1782430612656750592
author Eddens, Taylor
Song, Eunkyung
Ardura, Monica I.
Kolls, Jay K.
author_facet Eddens, Taylor
Song, Eunkyung
Ardura, Monica I.
Kolls, Jay K.
author_sort Eddens, Taylor
collection PubMed
description We report a case of Pneumocystis pneumonia in a 5-year-old male with Trisomy 21 and acute lymphoblastic leukemia. The lack of response to trimethoprim-sulfamethoxazole raised concerns for antimicrobial resistance. Further, diagnosis of Pneumocystis in this patient was complicated by a GMS-negative bronchoalveolar lavage despite molecular evidence of Pneumocystis infection.
format Online
Article
Text
id pubmed-4857217
institution National Center for Biotechnology Information
language English
publishDate 2016
publisher Elsevier
record_format MEDLINE/PubMed
spelling pubmed-48572172016-05-13 A protracted course of Pneumocystis pneumonia in the setting of an immunosuppressed child with GMS-negative bronchoalveolar lavage Eddens, Taylor Song, Eunkyung Ardura, Monica I. Kolls, Jay K. Med Mycol Case Rep Case Report We report a case of Pneumocystis pneumonia in a 5-year-old male with Trisomy 21 and acute lymphoblastic leukemia. The lack of response to trimethoprim-sulfamethoxazole raised concerns for antimicrobial resistance. Further, diagnosis of Pneumocystis in this patient was complicated by a GMS-negative bronchoalveolar lavage despite molecular evidence of Pneumocystis infection. Elsevier 2016-04-25 /pmc/articles/PMC4857217/ /pubmed/27182485 http://dx.doi.org/10.1016/j.mmcr.2016.04.004 Text en © 2016 The Authors http://creativecommons.org/licenses/by-nc-nd/4.0/ This is an open access article under the CC BY-NC-ND license (http://creativecommons.org/licenses/by-nc-nd/4.0/).
spellingShingle Case Report
Eddens, Taylor
Song, Eunkyung
Ardura, Monica I.
Kolls, Jay K.
A protracted course of Pneumocystis pneumonia in the setting of an immunosuppressed child with GMS-negative bronchoalveolar lavage
title A protracted course of Pneumocystis pneumonia in the setting of an immunosuppressed child with GMS-negative bronchoalveolar lavage
title_full A protracted course of Pneumocystis pneumonia in the setting of an immunosuppressed child with GMS-negative bronchoalveolar lavage
title_fullStr A protracted course of Pneumocystis pneumonia in the setting of an immunosuppressed child with GMS-negative bronchoalveolar lavage
title_full_unstemmed A protracted course of Pneumocystis pneumonia in the setting of an immunosuppressed child with GMS-negative bronchoalveolar lavage
title_short A protracted course of Pneumocystis pneumonia in the setting of an immunosuppressed child with GMS-negative bronchoalveolar lavage
title_sort protracted course of pneumocystis pneumonia in the setting of an immunosuppressed child with gms-negative bronchoalveolar lavage
topic Case Report
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4857217/
https://www.ncbi.nlm.nih.gov/pubmed/27182485
http://dx.doi.org/10.1016/j.mmcr.2016.04.004
work_keys_str_mv AT eddenstaylor aprotractedcourseofpneumocystispneumoniainthesettingofanimmunosuppressedchildwithgmsnegativebronchoalveolarlavage
AT songeunkyung aprotractedcourseofpneumocystispneumoniainthesettingofanimmunosuppressedchildwithgmsnegativebronchoalveolarlavage
AT arduramonicai aprotractedcourseofpneumocystispneumoniainthesettingofanimmunosuppressedchildwithgmsnegativebronchoalveolarlavage
AT kollsjayk aprotractedcourseofpneumocystispneumoniainthesettingofanimmunosuppressedchildwithgmsnegativebronchoalveolarlavage
AT eddenstaylor protractedcourseofpneumocystispneumoniainthesettingofanimmunosuppressedchildwithgmsnegativebronchoalveolarlavage
AT songeunkyung protractedcourseofpneumocystispneumoniainthesettingofanimmunosuppressedchildwithgmsnegativebronchoalveolarlavage
AT arduramonicai protractedcourseofpneumocystispneumoniainthesettingofanimmunosuppressedchildwithgmsnegativebronchoalveolarlavage
AT kollsjayk protractedcourseofpneumocystispneumoniainthesettingofanimmunosuppressedchildwithgmsnegativebronchoalveolarlavage

Ejemplares similares