Retrospective analysis of cohort database: Phenotypic variability in a large dataset of patients confirmed to have homozygous familial hypercholesterolemia

These data describe the phenotypic variability in a large cohort of patients confirmed to have homozygous familial hypercholesterolemia. Herein, we describe the observed relationship of treated low-density lipoprotein cholesterol with age. We also overlay the low-density lipoprotein receptor gene (L...

Descripción completa

Detalles Bibliográficos
Autores principales: Raal, Frederick J., Sjouke, Barbara, Hovingh, G. Kees, Isaac, Barton F.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2016
Materias:
Data Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4857223/
https://www.ncbi.nlm.nih.gov/pubmed/27182539
http://dx.doi.org/10.1016/j.dib.2016.04.004
_version_ 1782430614026190848
author Raal, Frederick J.
Sjouke, Barbara
Hovingh, G. Kees
Isaac, Barton F.
author_facet Raal, Frederick J.
Sjouke, Barbara
Hovingh, G. Kees
Isaac, Barton F.
author_sort Raal, Frederick J.
collection PubMed
description These data describe the phenotypic variability in a large cohort of patients confirmed to have homozygous familial hypercholesterolemia. Herein, we describe the observed relationship of treated low-density lipoprotein cholesterol with age. We also overlay the low-density lipoprotein receptor gene (LDLR) functional status with these phenotypic data. A full description of these data is available in our recent study published in Atherosclerosis, “Phenotype Diversity Among Patients With Homozygous Familial Hypercholesterolemia: A Cohort Study” (Raal et al., 2016) [1].
format Online
Article
Text
id pubmed-4857223
institution National Center for Biotechnology Information
language English
publishDate 2016
publisher Elsevier
record_format MEDLINE/PubMed
spelling pubmed-48572232016-05-13 Retrospective analysis of cohort database: Phenotypic variability in a large dataset of patients confirmed to have homozygous familial hypercholesterolemia Raal, Frederick J. Sjouke, Barbara Hovingh, G. Kees Isaac, Barton F. Data Brief Data Article These data describe the phenotypic variability in a large cohort of patients confirmed to have homozygous familial hypercholesterolemia. Herein, we describe the observed relationship of treated low-density lipoprotein cholesterol with age. We also overlay the low-density lipoprotein receptor gene (LDLR) functional status with these phenotypic data. A full description of these data is available in our recent study published in Atherosclerosis, “Phenotype Diversity Among Patients With Homozygous Familial Hypercholesterolemia: A Cohort Study” (Raal et al., 2016) [1]. Elsevier 2016-04-11 /pmc/articles/PMC4857223/ /pubmed/27182539 http://dx.doi.org/10.1016/j.dib.2016.04.004 Text en © 2016 The Authors http://creativecommons.org/licenses/by/4.0/ This is an open access article under the CC BY license (http://creativecommons.org/licenses/by/4.0/).
spellingShingle Data Article
Raal, Frederick J.
Sjouke, Barbara
Hovingh, G. Kees
Isaac, Barton F.
Retrospective analysis of cohort database: Phenotypic variability in a large dataset of patients confirmed to have homozygous familial hypercholesterolemia
title Retrospective analysis of cohort database: Phenotypic variability in a large dataset of patients confirmed to have homozygous familial hypercholesterolemia
title_full Retrospective analysis of cohort database: Phenotypic variability in a large dataset of patients confirmed to have homozygous familial hypercholesterolemia
title_fullStr Retrospective analysis of cohort database: Phenotypic variability in a large dataset of patients confirmed to have homozygous familial hypercholesterolemia
title_full_unstemmed Retrospective analysis of cohort database: Phenotypic variability in a large dataset of patients confirmed to have homozygous familial hypercholesterolemia
title_short Retrospective analysis of cohort database: Phenotypic variability in a large dataset of patients confirmed to have homozygous familial hypercholesterolemia
title_sort retrospective analysis of cohort database: phenotypic variability in a large dataset of patients confirmed to have homozygous familial hypercholesterolemia
topic Data Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4857223/
https://www.ncbi.nlm.nih.gov/pubmed/27182539
http://dx.doi.org/10.1016/j.dib.2016.04.004
work_keys_str_mv AT raalfrederickj retrospectiveanalysisofcohortdatabasephenotypicvariabilityinalargedatasetofpatientsconfirmedtohavehomozygousfamilialhypercholesterolemia
AT sjoukebarbara retrospectiveanalysisofcohortdatabasephenotypicvariabilityinalargedatasetofpatientsconfirmedtohavehomozygousfamilialhypercholesterolemia
AT hovinghgkees retrospectiveanalysisofcohortdatabasephenotypicvariabilityinalargedatasetofpatientsconfirmedtohavehomozygousfamilialhypercholesterolemia
AT isaacbartonf retrospectiveanalysisofcohortdatabasephenotypicvariabilityinalargedatasetofpatientsconfirmedtohavehomozygousfamilialhypercholesterolemia

Ejemplares similares