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Lactation undernutrition leads to multigenerational molecular programming of hypothalamic gene networks controlling reproduction

BACKGROUND: Reproductive success is dependent on development of hypothalamic circuits involving many hormonal systems working in concert to regulate gonadal function and sexual behavior. The timing of pubertal initiation and progression in mammals is likely influenced by the nutritional and metaboli...

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Detalles Bibliográficos
Autores principales: Kaczmarek, Monika M., Mendoza, Tamra, Kozak, Leslie P.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4857247/
https://www.ncbi.nlm.nih.gov/pubmed/27146259
http://dx.doi.org/10.1186/s12864-016-2615-4