Planning clinically relevant biomarker validation studies using the “number needed to treat” concept

PURPOSE: Despite an explosion of translational research to exploit biomarkers in diagnosis, prediction and prognosis, the impact of biomarkers on clinical practice has been limited. The elusiveness of clinical utility may partly originate when validation studies are planned, from a failure to articu...

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Detalles Bibliográficos
Autor principal: Day, Roger S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2016
Materias:
Methodology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4857295/
https://www.ncbi.nlm.nih.gov/pubmed/27146704
http://dx.doi.org/10.1186/s12967-016-0862-4

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4857295/
https://www.ncbi.nlm.nih.gov/pubmed/27146704
http://dx.doi.org/10.1186/s12967-016-0862-4

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