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Vitamin D and depression: A case series
INTRODUCTION: Over two-thirds of Canadians are deficient in vitamin D. Clinical overlap can compound diagnosis of depression in vitamin D deficient individuals. Citing high costs, the Ministry of Health has restricted routine vitamin D screening and hence is not feasible. OBJECTIVES: The current cas...
Autores principales: | , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
SAGE Publications
2014
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4857364/ https://www.ncbi.nlm.nih.gov/pubmed/27489667 http://dx.doi.org/10.1177/2050313X14561570 |
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author | Nadkarni, Pallavi S Odejayi, Gbolahan |
author_facet | Nadkarni, Pallavi S Odejayi, Gbolahan |
author_sort | Nadkarni, Pallavi S |
collection | PubMed |
description | INTRODUCTION: Over two-thirds of Canadians are deficient in vitamin D. Clinical overlap can compound diagnosis of depression in vitamin D deficient individuals. Citing high costs, the Ministry of Health has restricted routine vitamin D screening and hence is not feasible. OBJECTIVES: The current case series is an attempt to recognise the clinical overlap between depression and vitamin D deficiency in order to avoid unnecessary antidepressant prescriptions and to demonstrate the role of collaborative care in such patients. METHOD: After appropriate ethics approval 62 patients from an outpatient clinic were screened for the diagnosis of treatment resistant depression. Those who had predominant somatic complaints were further screened for organic factors and those with inadequate vitamin D levels were referred to family physicians for supplementation with vitamin D. RESULTS: More than 50% were detected deficient in vitamin D after our evaluation. They showed subjective improvement with vitamin D supplements. No modification of antidepressants was needed. CONCLUSION: Vitamin D deficiency should be suspected in depressed patients with prominent somatic symptoms and their treatment resistance should be reconsidered to avoid unnecessary exposure to mood stabilisers. Collaborating with primary care is advocated. LIMITATION: Co-prescription of an antidepressant is a confounder in our case series, and we propose more organised studies with objective rating scales. |
format | Online Article Text |
id | pubmed-4857364 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2014 |
publisher | SAGE Publications |
record_format | MEDLINE/PubMed |
spelling | pubmed-48573642016-08-03 Vitamin D and depression: A case series Nadkarni, Pallavi S Odejayi, Gbolahan SAGE Open Med Case Rep Case Report INTRODUCTION: Over two-thirds of Canadians are deficient in vitamin D. Clinical overlap can compound diagnosis of depression in vitamin D deficient individuals. Citing high costs, the Ministry of Health has restricted routine vitamin D screening and hence is not feasible. OBJECTIVES: The current case series is an attempt to recognise the clinical overlap between depression and vitamin D deficiency in order to avoid unnecessary antidepressant prescriptions and to demonstrate the role of collaborative care in such patients. METHOD: After appropriate ethics approval 62 patients from an outpatient clinic were screened for the diagnosis of treatment resistant depression. Those who had predominant somatic complaints were further screened for organic factors and those with inadequate vitamin D levels were referred to family physicians for supplementation with vitamin D. RESULTS: More than 50% were detected deficient in vitamin D after our evaluation. They showed subjective improvement with vitamin D supplements. No modification of antidepressants was needed. CONCLUSION: Vitamin D deficiency should be suspected in depressed patients with prominent somatic symptoms and their treatment resistance should be reconsidered to avoid unnecessary exposure to mood stabilisers. Collaborating with primary care is advocated. LIMITATION: Co-prescription of an antidepressant is a confounder in our case series, and we propose more organised studies with objective rating scales. SAGE Publications 2014-12-04 /pmc/articles/PMC4857364/ /pubmed/27489667 http://dx.doi.org/10.1177/2050313X14561570 Text en © The Author(s) 2014 http://creativecommons.org/licenses/by-nc/3.0/ This article is distributed under the terms of the Creative Commons Attribution-NonCommercial 3.0 License (http://www.creativecommons.org/licenses/by-nc/3.0/) which permits non-commercial use, reproduction and distribution of the work without further permission provided the original work is attributed as specified on the SAGE and Open Access page(http://www.uk.sagepub.com/aboutus/openaccess.htm). |
spellingShingle | Case Report Nadkarni, Pallavi S Odejayi, Gbolahan Vitamin D and depression: A case series |
title | Vitamin D and depression: A case series |
title_full | Vitamin D and depression: A case series |
title_fullStr | Vitamin D and depression: A case series |
title_full_unstemmed | Vitamin D and depression: A case series |
title_short | Vitamin D and depression: A case series |
title_sort | vitamin d and depression: a case series |
topic | Case Report |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4857364/ https://www.ncbi.nlm.nih.gov/pubmed/27489667 http://dx.doi.org/10.1177/2050313X14561570 |
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