Analytic framework for peptidomics applied to large-scale neuropeptide identification

Large-scale mass spectrometry-based peptidomics for drug discovery is relatively unexplored because of challenges in peptide degradation and identification following tissue extraction. Here we present a streamlined analytical pipeline for large-scale peptidomics. We developed an optimized sample pre...

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Detalles Bibliográficos
Autores principales: Secher, Anna, Kelstrup, Christian D., Conde-Frieboes, Kilian W., Pyke, Charles, Raun, Kirsten, Wulff, Birgitte S., Olsen, Jesper V.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4857386/
https://www.ncbi.nlm.nih.gov/pubmed/27142507
http://dx.doi.org/10.1038/ncomms11436

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4857386/
https://www.ncbi.nlm.nih.gov/pubmed/27142507
http://dx.doi.org/10.1038/ncomms11436

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