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Analytic framework for peptidomics applied to large-scale neuropeptide identification
Large-scale mass spectrometry-based peptidomics for drug discovery is relatively unexplored because of challenges in peptide degradation and identification following tissue extraction. Here we present a streamlined analytical pipeline for large-scale peptidomics. We developed an optimized sample pre...
Autores principales: | Secher, Anna, Kelstrup, Christian D., Conde-Frieboes, Kilian W., Pyke, Charles, Raun, Kirsten, Wulff, Birgitte S., Olsen, Jesper V. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4857386/ https://www.ncbi.nlm.nih.gov/pubmed/27142507 http://dx.doi.org/10.1038/ncomms11436 |
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