The effect of high glucose on the inhibitory action of C21, a selective AT2R agonist, of LPS-stimulated tissue factor expression in human mononuclear cells

BACKGROUND: Intimate links connect tissue factor (TF), the principal initiator of the clotting cascade, to inflammation, a cross-talk amplified by locally generated Angiotensin (AT) II, the effector arm of the Renin Angiotensin System (RAS). C21, a selective AT2R agonist, downregulates the transcrip...

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Detalles Bibliográficos
Autores principales: Balia, Cristina, Scalise, Valentina, Cianchetti, Silvana, Faita, Francesca, Neri, Tommaso, Carnicelli, Vittoria, Zucchi, Riccardo, Celi, Alessandro, Pedrinelli, Roberto
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2016
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4857424/
https://www.ncbi.nlm.nih.gov/pubmed/27152091
http://dx.doi.org/10.1186/s12950-016-0123-6

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