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Modulating the Amyloidogenesis of α-Synuclein
Alphα-synuclein is found in the neuronal cells but its native function is not well known. While α-synuclein is an intrinsically disordered protein that adopts a helical conformation upon membrane binding, numerous studies have shown that oligomeric b-forms of this protein are cytotoxic. This respons...
| Autores principales: | , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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Bentham Science Publishers
2016
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4857621/ https://www.ncbi.nlm.nih.gov/pubmed/26517049 http://dx.doi.org/10.2174/1570159X13666151030103153 |