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In vitro modeling of COPD inflammation and limitation of p38 inhibitor – SB203580

BACKGROUND: Systemic inflammation and steroid resistance are the hallmarks of COPD. We examined the impact of p38 inhibitor (SB203580) in in vitro assays of systemic inflammation using pulmonary cells and patients’ sera. OBJECTIVE AND METHODS: Data from 66 COPD patients and 15 age-/sex-matched healt...

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Detalles Bibliográficos
Autores principales: Meng, Aihong, Zhang, Xiaopeng, Wu, Siyu, Wu, Mingxia, Li, Jing, Yan, Xixin, Kopec-Harding, Kamilla, Wu, Jiakai
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dove Medical Press 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4857829/
https://www.ncbi.nlm.nih.gov/pubmed/27199554
http://dx.doi.org/10.2147/COPD.S99810

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