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Inflammatory Response to Lipopolysaccharide on the Ocular Surface in a Murine Dry Eye Model
PURPOSE: Toll-like receptor 4 (TLR4) alerts cells to the presence of bacteria by initiating an inflammatory response. We hypothesize that disruption of the ocular surface barrier in dry eye enhances TLR4 signaling. This study determined whether dry eye enhances expression of inflammatory mediators i...
Autores principales: | Simmons, Ken T., Xiao, Yangyan, Pflugfelder, Stephen C., de Paiva, Cintia S. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
The Association for Research in Vision and Ophthalmology
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4857831/ https://www.ncbi.nlm.nih.gov/pubmed/27136463 http://dx.doi.org/10.1167/iovs.15-18396 |
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