Cargando…
Plasma Kallikrein Mediates Vascular Endothelial Growth Factor–Induced Retinal Dysfunction and Thickening
PURPOSE: Plasma kallikrein is a serine protease and circulating component of inflammation, which exerts clinically significant effects on vasogenic edema. This study examines the role of plasma kallikrein in VEGF-induced retinal edema. METHODS: Intravitreal injections of VEGF and saline vehicle were...
Autores principales: | Clermont, Allen, Murugesan, Nivetha, Zhou, Qunfang, Kita, Takeshi, Robson, Peter A., Rushbrooke, Louise J., Evans, D. Michael, Aiello, Lloyd Paul, Feener, Edward P. |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
The Association for Research in Vision and Ophthalmology
2016
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4857835/ https://www.ncbi.nlm.nih.gov/pubmed/27138737 http://dx.doi.org/10.1167/iovs.15-18272 |
Ejemplares similares
-
Plasma Kallikrein Mediates Retinal Vascular Dysfunction and Induces Retinal Thickening in Diabetic Rats
por: Clermont, Allen, et al.
Publicado: (2011) -
Targeting Plasma Kallikrein With a Novel Bicyclic Peptide Inhibitor (THR-149) Reduces Retinal Thickening in a Diabetic Rat Model
por: Van Bergen, Tine, et al.
Publicado: (2021) -
Vascular Density of Deep, Intermediate and Superficial Vascular Plexuses Are Differentially Affected by Diabetic Retinopathy Severity
por: Ashraf, Mohamed, et al.
Publicado: (2020) -
Pharmacological suppression of the kallikrein kinin system with KVD900: An orally available plasma kallikrein inhibitor for the on‐demand treatment of hereditary angioedema
por: Duckworth, Edward J., et al.
Publicado: (2022) -
MicroRNA-92a-3p Regulates Retinal Angiogenesis by Targeting SGK3 in Vascular Endothelial Cells
por: Cui, Yamei, et al.
Publicado: (2022)