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Risperidone-induced Gingival Bleeding in a Pediatric Case: A Dose-dependent Side Effect

There are several case reports on risperidone-related bleeding; however, to our knowledge, there is no report about gingival bleeding associated with risperidone in the literature. We presented a case who experienced gingival bleeding when risperidone dose was increased to 0.5 mg/day, and subsided a...

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Detalles Bibliográficos
Autores principales: Hergüner, Sabri, Özayhan, Hatice Yardım, Erdur, Emire Aybuke
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Korean College of Neuropsychopharmacology 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4857868/
https://www.ncbi.nlm.nih.gov/pubmed/27121433
http://dx.doi.org/10.9758/cpn.2016.14.2.210
Descripción
Sumario:There are several case reports on risperidone-related bleeding; however, to our knowledge, there is no report about gingival bleeding associated with risperidone in the literature. We presented a case who experienced gingival bleeding when risperidone dose was increased to 0.5 mg/day, and subsided after decreasing the dose to 0.25 mg/day, suggesting a dose-dependent side-effect. The bleeding side effect of risperidone might be caused by several mechanisms, including 5-hydroxytryptamine 2A receptor antagonism. Although bleeding associated with risperidone is rarely reported, clinicians should be aware of this side effect.