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High CerS5 expression levels associate with reduced patient survival and transition from apoptotic to autophagy signalling pathways in colorectal cancer

Ceramide synthase 5 is involved in the de novo synthesis of ceramide, a sphingolipid involved in cell death and proliferation. In this study, we investigated the role of ceramide synthase 5 in colorectal cancer by examining ceramide synthase 5 expression, clinico‐pathological parameters and associat...

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Detalles Bibliográficos
Autores principales: Fitzgerald, Seán, Sheehan, Katherine M, Espina, Virginia, O'Grady, Anthony, Cummins, Robert, Kenny, Dermot, Liotta, Lance, O'Kennedy, Richard, Kay, Elaine W, Kijanka, Gregor S
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4858121/
https://www.ncbi.nlm.nih.gov/pubmed/27499893
http://dx.doi.org/10.1002/cjp2.5