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High expression of podoplanin in squamous cell carcinoma of the tongue occurs predominantly in patients ≤40 years but does not correlate with tumour spread
More than 30% of patients with squamous cell carcinoma (SCC) of the mobile tongue have clinically undetectable lymph node metastasis. Tumour cells can spread as single cells or collectively. A protein known to play a role in both processes is podoplanin, which is expressed in endothelial cells not o...
Autores principales: | Sgaramella, Nicola, Lindell Jonsson, Eva, Boldrup, Linda, Califano, Luigi, Coates, Philip J, Tartaro, Gianpaolo, Lo Muzio, Lorenzo, Fåhraeus, Robin, Colella, Giuseppe, Dell'Aversana Orabona, Giovanni, Loljung, Lotta, Santagata, Mario, Rossiello, Riccardo, Wilms, Torben, Danielsson, Karin, Laurell, Göran, Nylander, Karin |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
John Wiley and Sons Inc.
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4858125/ https://www.ncbi.nlm.nih.gov/pubmed/27499910 http://dx.doi.org/10.1002/cjp2.28 |
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