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Unilateral Partial Nephrectomy with Warm Ischemia Results in Acute Hypoxia Inducible Factor 1-Alpha (HIF-1α) and Toll-Like Receptor 4 (TLR4) Overexpression in a Porcine Model

PURPOSE: Ischemia/reperfusion (I/R) during partial nephrectomy (PN) contributes to acute kidney injury (AKI), which is inaccurately assessed using existent clinical markers of renal function. We evaluated I/R-related changes in expression in hypoxia inducible factor 1α (HIF-1α) and toll-like recepto...

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Detalles Bibliográficos
Autores principales:	Zhang, Zhiyong, Haimovich, Beatrice, Kwon, Young Suk, Lu, Tyler, Fyfe-Kirschner, Billie, Olweny, Ephrem Odoy
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2016
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4858142/ https://www.ncbi.nlm.nih.gov/pubmed/27149666 http://dx.doi.org/10.1371/journal.pone.0154708

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