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Carboxyl-Terminal SSLKG Motif of the Human Cystinosin-LKG Plays an Important Role in Plasma Membrane Sorting

Cystinosin mediates an ATP-dependent cystine efflux from lysosomes and causes, if mutated, nephropathic cystinosis, a rare inherited lysosomal storage disease. Alternative splicing of the last exon of the cystinosin sequence produces the cystinosin-LKG isoform that is characterized by a different C-...

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Detalles Bibliográficos
Autores principales:	Bellomo, Francesco, Taranta, Anna, Petrini, Stefania, Venditti, Rossella, Rocchetti, Maria Teresa, Rega, Laura Rita, Corallini, Serena, Gesualdo, Loreto, De Matteis, Maria Antonietta, Emma, Francesco
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2016
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4858208/ https://www.ncbi.nlm.nih.gov/pubmed/27148969 http://dx.doi.org/10.1371/journal.pone.0154805

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