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Insulin Signaling in Insulin Resistance States and Cancer: A Modeling Analysis
Insulin resistance is the common denominator of several diseases including type 2 diabetes and cancer, and investigating the mechanisms responsible for insulin signaling impairment is of primary importance. A mathematical model of the insulin signaling network (ISN) is proposed and used to investiga...
Autores principales: | Bertuzzi, Alessandro, Conte, Federica, Mingrone, Geltrude, Papa, Federico, Salinari, Serenella, Sinisgalli, Carmela |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4858213/ https://www.ncbi.nlm.nih.gov/pubmed/27149630 http://dx.doi.org/10.1371/journal.pone.0154415 |
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