Discovery of Genetic Variation on Chromosome 5q22 Associated with Mortality in Heart Failure

Failure of the human heart to maintain sufficient output of blood for the demands of the body, heart failure, is a common condition with high mortality even with modern therapeutic alternatives. To identify molecular determinants of mortality in patients with new-onset heart failure, we performed a...

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Detalles Bibliográficos
Autores principales: Smith, J. Gustav, Felix, Janine F., Morrison, Alanna C., Kalogeropoulos, Andreas, Trompet, Stella, Wilk, Jemma B., Gidlöf, Olof, Wang, Xinchen, Morley, Michael, Mendelson, Michael, Joehanes, Roby, Ligthart, Symen, Shan, Xiaoyin, Bis, Joshua C., Wang, Ying A., Sjögren, Marketa, Ngwa, Julius, Brandimarto, Jeffrey, Stott, David J., Aguilar, David, Rice, Kenneth M., Sesso, Howard D., Demissie, Serkalem, Buckley, Brendan M., Taylor, Kent D., Ford, Ian, Yao, Chen, Liu, Chunyu, Sotoodehnia, Nona, van der Harst, Pim, Stricker, Bruno H. Ch., Kritchevsky, Stephen B., Liu, Yongmei, Gaziano, J. Michael, Hofman, Albert, Moravec, Christine S., Uitterlinden, André G., Kellis, Manolis, van Meurs, Joyce B., Margulies, Kenneth B., Dehghan, Abbas, Levy, Daniel, Olde, Björn, Psaty, Bruce M., Cupples, L. Adrienne, Jukema, J. Wouter, Djousse, Luc, Franco, Oscar H., Boerwinkle, Eric, Boyer, Laurie A., Newton-Cheh, Christopher, Butler, Javed, Vasan, Ramachandran S., Cappola, Thomas P., Smith, Nicholas L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2016
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4858216/
https://www.ncbi.nlm.nih.gov/pubmed/27149122
http://dx.doi.org/10.1371/journal.pgen.1006034

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