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A Regional Reduction in I(to) and I(KACh) in the Murine Posterior Left Atrial Myocardium Is Associated with Action Potential Prolongation and Increased Ectopic Activity
BACKGROUND: The left atrial posterior wall (LAPW) is potentially an important area for the development and maintenance of atrial fibrillation. We assessed whether there are regional electrical differences throughout the murine left atrial myocardium that could underlie regional differences in arrhyt...
Autores principales: | Holmes, Andrew P., Yu, Ting Y., Tull, Samantha, Syeda, Fahima, Kuhlmann, Stefan M., O’Brien, Sian-Marie, Patel, Pushpa, Brain, Keith L., Pavlovic, Davor, Brown, Nigel A., Fabritz, Larissa, Kirchhof, Paulus |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4858288/ https://www.ncbi.nlm.nih.gov/pubmed/27149380 http://dx.doi.org/10.1371/journal.pone.0154077 |
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