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Cell-of-Origin-Specific 3D Genome Structure Acquired during Somatic Cell Reprogramming

Forced expression of reprogramming factors can convert somatic cells into induced pluripotent stem cells (iPSCs). Here we studied genome topology dynamics during reprogramming of different somatic cell types with highly distinct genome conformations. We find large-scale topologically associated doma...

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Detalles Bibliográficos
Autores principales:	Krijger, Peter Hugo Lodewijk, Di Stefano, Bruno, de Wit, Elzo, Limone, Francesco, van Oevelen, Chris, de Laat, Wouter, Graf, Thomas
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Cell Press 2016
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4858530/ https://www.ncbi.nlm.nih.gov/pubmed/26971819 http://dx.doi.org/10.1016/j.stem.2016.01.007

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