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Clonal B cells in Waldenström's macroglobulinemia exhibit functional features of chronic active B-cell receptor signaling

Waldenström's macroglobulinemia (WM) is a B-cell non-Hodgkin's lymphoma (B-NHL) characterized by immunoglobulin M (IgM) monoclonal gammopathy and the medullary expansion of clonal lymphoplasmacytic cells. Neoplastic transformation has been partially attributed to hyperactive MYD88 signalin...

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Detalles Bibliográficos
Autores principales:	Argyropoulos, K V, Vogel, R, Ziegler, C, Altan-Bonnet, G, Velardi, E, Calafiore, M, Dogan, A, Arcila, M, Patel, M, Knapp, K, Mallek, C, Hunter, Z R, Treon, S P, van den Brink, M R M, Palomba, M L
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group 2016
Materias:	Original Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4858584/ https://www.ncbi.nlm.nih.gov/pubmed/26867669 http://dx.doi.org/10.1038/leu.2016.8

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