Mouse mesenchymal stem cells inhibit high endothelial cell activation and lymphocyte homing to lymph nodes by releasing TIMP-1

Mesenchymal stem cells (MSC) represent a promising therapeutic approach in many diseases in view of their potent immunomodulatory properties, which are only partially understood. Here, we show that the endothelium is a specific and key target of MSC during immunity and inflammation. In mice, MSC inh...

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Detalles Bibliográficos
Autores principales: Zanotti, L, Angioni, R, Calì, B, Soldani, C, Ploia, C, Moalli, F, Gargesha, M, D'Amico, G, Elliman, S, Tedeschi, G, Maffioli, E, Negri, A, Zacchigna, S, Sarukhan, A, Stein, J V, Viola, A
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4858586/
https://www.ncbi.nlm.nih.gov/pubmed/26898191
http://dx.doi.org/10.1038/leu.2016.33

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