Quantification of topological features in cell meshes to explore E-cadherin dysfunction

In cancer, defective E-cadherin leads to cell detachment, migration and metastization. Further, alterations mediated by E-cadherin dysfunction affect cell topology and tissue organization. Herein, we propose a novel quantitative approach, based on microscopy images, to analyse abnormal cellular dist...

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Detalles Bibliográficos
Autores principales: Mestre, Tânia, Figueiredo, Joana, Ribeiro, Ana Sofia, Paredes, Joana, Seruca, Raquel, Sanches, João Miguel
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4858654/
https://www.ncbi.nlm.nih.gov/pubmed/27151223
http://dx.doi.org/10.1038/srep25101

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4858654/
https://www.ncbi.nlm.nih.gov/pubmed/27151223
http://dx.doi.org/10.1038/srep25101

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