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Cetuximab-modified mesoporous silica nano-medicine specifically targets EGFR-mutant lung cancer and overcomes drug resistance

Drug resistance to tyrosine kinase inhibitor (TKI) is the main obstacle for efficient treatment of epidermal growth factor receptor (EGFR)-mutant lung cancer patients. Here we design a cetuximab-capped mesoporous silica nanoparticle (MP-SiO(2) NP) as the drug carrier to specifically target EGFR-muta...

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Detalles Bibliográficos
Autores principales:	Wang, Yuetong, Huang, Hsin-Yi, Yang, Liu, Zhang, Zhanxia, Ji, Hongbin
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group 2016
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4858690/ https://www.ncbi.nlm.nih.gov/pubmed/27151505 http://dx.doi.org/10.1038/srep25468

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