Convergent Transcription of Interferon-stimulated Genes by TNF-α and IFN-α Augments Antiviral Activity against HCV and HEV

IFN-α has been used for decades to treat chronic hepatitis B and C, and as an off-label treatment for some cases of hepatitis E virus (HEV) infection. TNF-α is another important cytokine involved in inflammatory disease, which can interact with interferon signaling. Because interferon-stimulated gen...

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Detalles Bibliográficos
Autores principales: Wang, Wenshi, Xu, Lei, Brandsma, Johannes H., Wang, Yijin, Hakim, Mohamad S., Zhou, Xinying, Yin, Yuebang, Fuhler, Gwenny M., van der Laan, Luc J. W., van der Woude, C. Janneke, Sprengers, Dave, Metselaar, Herold J., Smits, Ron, Poot, Raymond A., Peppelenbosch, Maikel P., Pan, Qiuwei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4858707/
https://www.ncbi.nlm.nih.gov/pubmed/27150018
http://dx.doi.org/10.1038/srep25482

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