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STIM1-dependent Ca(2+) microdomains are required for myofilament remodeling and signaling in the heart
In non-excitable cells stromal interaction molecule 1 (STIM1) is a key element in the generation of Ca(2+) signals that lead to gene expression, migration and cell proliferation. A growing body of literature suggests that STIM1 plays a key role in the development of pathological cardiac hypertrophy....
Autores principales: | Parks, Cory, Alam, Mohammad Afaque, Sullivan, Ryan, Mancarella, Salvatore |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4858716/ https://www.ncbi.nlm.nih.gov/pubmed/27150728 http://dx.doi.org/10.1038/srep25372 |
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