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Mapping Local Cytosolic Enzymatic Activity in Human Esophageal Mucosa with Porous Silicon Nanoneedles
Porous silicon nanoneedles can map Cathepsin B activity across normal and tumor human esophageal mucosa. Assembling a peptide‐based Cathepsin B cleavable sensor over a large array of nanoneedles allows the discrimination of cancer cells from healthy ones in mixed culture. The same sensor applied to...
Autores principales: | Chiappini, Ciro, Campagnolo, Paola, Almeida, Carina S., Abbassi‐Ghadi, Nima, Chow, Lesley W., Hanna, George B., Stevens, Molly M. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
John Wiley and Sons Inc.
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4858817/ https://www.ncbi.nlm.nih.gov/pubmed/26197973 http://dx.doi.org/10.1002/adma.201501304 |
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