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Differences in PfEMP1s recognized by antibodies from patients with uncomplicated or severe malaria
BACKGROUND: Plasmodium falciparum erythrocyte membrane protein 1 (PfEMP1) variants are encoded by var genes and mediate pathogenic cytoadhesion and antigenic variation in malaria. PfEMP1s can be broadly divided into three principal groups (A, B and C) and they contain conserved arrangements of funct...
Autores principales: | Duffy, Michael F., Noviyanti, Rintis, Tsuboi, Takafumi, Feng, Zhi-Ping, Trianty, Leily, Sebayang, Boni F., Takashima, Eizo, Sumardy, Fransisca, Lampah, Daniel A., Turner, Louise, Lavstsen, Thomas, Fowkes, Freya J. I., Siba, Peter, Rogerson, Stephen J., Theander, Thor G., Marfurt, Jutta, Price, Ric N., Anstey, Nicholas M., Brown, Graham V., Papenfuss, Anthony T. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4858840/ https://www.ncbi.nlm.nih.gov/pubmed/27149991 http://dx.doi.org/10.1186/s12936-016-1296-4 |
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