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Parallel computation of genome-scale RNA secondary structure to detect structural constraints on human genome
BACKGROUND: RNA secondary structure around splice sites is known to assist normal splicing by promoting spliceosome recognition. However, analyzing the structural properties of entire intronic regions or pre-mRNA sequences has been difficult hitherto, owing to serious experimental and computational...
| Autores principales: | , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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BioMed Central
2016
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4858847/ https://www.ncbi.nlm.nih.gov/pubmed/27153986 http://dx.doi.org/10.1186/s12859-016-1067-9 |